Project mission
Project mission
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Our mission is to protect the health of individuals with treatment-resistant schizophrenia by understanding how certain antispychotic medications, like clozapine, affect bacteria in the mouth.
This research focuses on finding out why patients on antipsychotics are more likely to develop infections and how we can detect harmful bacteria early to prevent serious illnesses. By exploring this connection, we aim to develop simple, non-invasive tests that could improve health outcomes and make life better for these patients.
Why we need healthy volunteers
Why we need healthy volunteers
Healthy volunteers are essential for our research. By comparing the bacteria in the mouths of healthy individuals to those in patients with schizophrenia, we can better understand how medications like clozapine affect the balance of good and harmful bacteria. Your participation helps create a "baseline" that allows us to detect changes and uncover pathogens.
Why your participation matters
Why your participation matters
Your involvement is invaluable in finding better ways to protect vulnerable patients. By contributing, you help advance medical research that could lead to early detection of harmful bacteria, improved health outcomes, and life-saving solutions.
1. Understanding Oral Bacteria
1. Understanding Oral Bacteria
Description: Study bacteria changes in the oral cavity in patients with a diagnosis of schizophrenia prescribed the antipsychotic clozapine.
Aim: Identify harmful bacteria associated with clozapine use.
2. Detecting Persistent Bacteria
2. Detecting Persistent Bacteria
Description: Determine if harmful bacteria in the oral cavity are temporary or if they persist.
Aim: Assess long-term bacterial presence in patients with a diagnosis of schizophrenia prescribed the antipsychotic clozapine.
3. Track Pathogens
3. Track Pathogens
Description: Investigate how harmful bacteria identified in the oral cavity can spread and cause infections.
Aim: Uncover the impact of oral bacteria’s on health and inflammation.
4. Developing Early Diagnostic Tests
4. Developing Early Diagnostic Tests
Description: Create simple rapid tests to detect harmful bacteria in the oral cavity early.
Aim: Prevent infections with non-invasive saliva-based diagnostics and early intervention.
Have any questions?
Have any questions?
Please contact f.mcdonagh4@universityofgalway.ie for more information about the study and for enrolment to the study.
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